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Author: Dana Bartlett, BSN, MSN, MA, CSPI
(Click author's name for bio)

CE: 2.5 hours Pharmacology: 2.5 hours
Rated 4.7 out of 5.0 based on 1100 reviews

Course Summary

Levetiracetam is a second-generation anticonvulsant that has labeled uses as an adjunctive treatment for myoclonic seizures, partial-onset seizures, and primary generalized tonic-clonic seizures. The mechanism of action by which levetiracetam provides an anticonvulsant effect is not known. As with all anticonvulsant agents, levetiracetam is recommended to start and to be titrated at a very low dose because of the known risk of skin rashes and the potential for Stevens-Johnson syndrome and toxic epidermal necrolysis, although the reported incidence of skin rash is lower with levetiracetam than with certain anticonvulsant drugs, such as lamotrigine. A basic pharmacological profile of levetiracetam, a detailed discussion of specific issues regarding its use, and a brief focus on levetiracetam overdose are discussed.

Course Format


Course Syllabus

I.              Introduction

II.           Pharmacological Profile

1.     Category

2.     Mechanism of Action

3.     Uses

4.     Dosing

5.     Available Forms

6.     Contraindications

7.     Warnings

8.     Adverse Effects

9.     Pregnancy and Breastfeeding

10.    Dietary Issues

III.         Levetiracetam Overdose

IV.          Clinical Pearls: Levetiracetam

V.            Case Study

1.   Discussion

VI.          Summary


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