I. Introduction
II. Pharmacological Profile
1. Drug Category
2. Mechanism of Action
3. Labeled Uses
4. Off-Label Uses
5. Dosing
6. Available Forms
7. Dosing Adjustment: Geriatric Patients
8. Dosing Adjustment: Hepatic Impairment
9. Dosing Adjustment: Renal Impairment
10. US Boxed Warning
11. Contraindications
12. Adverse Effects
13. Warnings and Precautions
14. Pregnancy and Breastfeeding
15. Drug-drug Interactions
III. Clinical Pearls: Duloxetine
IV. Duloxetine Overdose
V. Case Study: Duloxetine
1. Discussion
VI. Summary