Course Summary

Allogeneic stem cell transplantation is a medical procedure used primarily in the treatment of various hematologic malignancies and other disorders, where healthy stem cells from a genetically matched donor are transplanted into a recipient. These stem cells, typically derived from bone marrow, peripheral blood, or umbilical cord blood, possess the ability to regenerate and rebuild the recipient’s immune system, replacing damaged or dysfunctional cells. The process involves conditioning the recipient’s body with chemotherapy and/or radiation therapy to eliminate existing diseased cells and make space for the donor cells. While allogeneic transplantation offers the potential for long-term remission or cure, it also carries risks of complications, such as graft-versus-host disease (GVHD), where the donor cells attack the recipient’s tissues, and infections due to weakened immunity, necessitating careful monitoring and management post-transplantation. Common disease states that may require stem cell transplantation include leukemia, lymphoma, and multiple myeloma, especially when standard treatments have failed or the disease is in advanced stages.

Course Format


Course Syllabus

  • Introduction
  • Indications for Transplant
    • Hematologic Malignancies
    • Bone Marrow Failure Syndromes
    • Genetic Disorders
    • Autoimmune Disorders
  • Hematopoietic Stem Cell Collection
    • Donor Preparation – Allogeneic PBSC
    • PBSC Collection Day
  • Receipt of Peripheral Blood Stem Cells
  • Complications of Hematopoietic Stem Cell Transplantation
    • Pre-engraftment Complications
    • Early Post-engraftment Complications
    • Late Post-engraftment Complications
  • National Bone Marrow Donor Program (NMDP)
  • Case Study
  • Summary


Richard Daniels, PharmD, BCPS

Richard “Cole” Daniels earned his Doctor of Pharmacy(PharmD) from the Skaggs School of Pharmacy at the University of Montana in 2018. Throughout pharmacy school he completed a 3-year internship at Community Medical Center in Missoula, Montana in which he gained valuable experience in an acute care setting. Cole currently serves as a psychiatric clinical staff pharmacist at the Montana State Hospital. He has over 11 years of pharmacy experience having worked in several settings including retail, acute care, and inpatient psychiatric care. Cole has a diverse set of interests. However, acute care medicine, infectious disease, pain management, and asthma/COPD are a primary focus of his at the Montana State Hospital. He obtained board certification as a certified pharmacotherapy specialist in the Spring of 2022.

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