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Zonisamide

Author: Abimbola Farinde, PhD., PharmD

CE: 2.5 hours Pharmacology: 2.5 hours
Rated 4.7 out of 5.0 based on 4343 reviews

Course Summary

Zonisamide is an antiepileptic drug available for use with children and adults. Zonisamide is considered a broad-spectrum anticonvulsant with proven efficacy in randomized, controlled trials as add-on therapy for focal and generalized seizures. There has been clinical experience that indicates that zonisamide is an effective monotherapy for seizures, as well. Zonisamide is also being used as off-label drug therapy for disorders such as alcohol use, bipolar disorder, and binge-eating disorder. Zonisamide is generally known to offer improved versatility with less side effects than other antiepileptic drugs; however, a greater clinical understanding of zonisamide is needed. Rare, life-threatening reactions to zonisamide have been reported. These reactions include Stevens-Johnson syndrome and toxic epidermal necrolysis.

Course Format

Homestudy

Course Syllabus

I.    Introduction

II.    Pharmacological Profile

1. Mechanism of Action and Uses
2. Dosing and Available Forms
3. Contraindications and Warnings
4. Adverse Reactions
5. Pregnancy and Breastfeeding
6. Dietary Issues

III.    Clinical Pearls: Zonisamide

1. Zonisamide Uses and Efficacy
2. Warnings, Precautions and Contraindications
3. Zonisamide Overdose

IV.    Case Study: Stevens-Johnson Syndrome

    Discussion

V.    Summary

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