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Topiramate

Author: Dana Bartlett, BSN, MSN, MA, CSPI
(Click author's name for bio)

CE: 2.5 hours Pharmacology: 2.5 hours
Rated 4.7 out of 5.0 based on 572 reviews

Course Summary

Topiramate is an anticonvulsant drug that has been approved for the treatment of various kinds of epilepsy. It has also been studied as a treatment for neurological and psychiatric disorders. The mechanisms by which topiramate acts as an anticonvulsant are not completely understood. The pharmacokinetic interactions of topiramate with other medications, especially other antiepileptics and medications affecting the central nervous system, should be understood and monitored when prescribing topiramate.

Course Format

Homestudy

Course Syllabus

I.              Introduction

II.           Pharmacological Profile

1.         Drug Category

2.         Mechanism of Action

3.         Uses

4.         Dosing: Adult

5.         Dosing: Geriatric

6.         Dosing Adjustment: Hepatic Impairment

7.         Dosing Adjustment: Rental Impairment

8.         Available Forms

9.         Contraindications

10.     US Boxed Warning

11.     Warnings

12.     Adverse Effects

13.     Drug Interactions

14.     Pregnancy and Breastfeeding

III.        Clinical Pearls: Topiramate

1.   Monotherapy

2.   Adjunctive Therapy

3.   Lennox-Gastaut Syndrome

4.   Migraine Headache

IV.         Topiramate Overdose

1.   Treatment of Overdose

V.            Case Study

1.   Discussion

VI.         Summary

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