I. Introduction
II. Smoking and Tobacco Use in the United States
III. Nicotine
IV. Pathophysiology of Acute Nicotine Craving
1. Tobacco Use Disorder
V. Diagnosis of Tobacco Use Disorder
VI. Tobacco Withdrawal
VII. Smoking Cessation: Basic Principles
VIII. Risks of Smoking Cessation
1. Cough and Mouth Ulcers
2. Mental Illness
3. Weight Gain
4. Cardiovascular Disease
IX. Beginning the Process of Smoking Cessation
1. Ask
2. Advise
3. Assess
4. Assist
5. Arrange
X. Aids to Smoking Cessation
1. Behavioral Interventions
XI. Pharmacotherapy and Smoking Cessation
1. Bupropion
2. Nicotine Replacement Therapy (NRT)
3. Varenicline
XII. Alternative Therapies for Smoking Cessation
1. Acupuncture
2. Hypnosis
3. E-cigarettes
XIII. Smoking Cessation: Failure and Success
1. Patient Resources
XIV. Case Study: Smoking Cessation
XV. Summary