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Diabetes Type I - Current Modalities of Treatment

Author: Kellie Wilson, PharmD

CE: 2.5 hours Pharmacology: 1 hour
Rated 4.7 out of 5.0 based on 3500 reviews

Course Summary

Type 1 diabetes mellitus is a chronic, autoimmune disease that occurs due to pancreas beta cell destruction and insulin deficiency. Symptoms of type 1 diabetes result from high levels of blood glucose which is also known as hyperglycemia. Type 1 diabetes generally begins in children and adolescents however can also develop later on in adults. The etiology of type 1 diabetes remains unknown however it is widely believed to develop because of T cell-mediated destruction of beta cells and autoantibody activity that affect the production of insulin. Environmental triggers and genetic factors will influence the type of autoantibody that influences disease progression. A cure for diabetes is currently not available and disease management depends on lifelong insulin injections. Varied approaches to insulin administration may be introduced to type 1 diabetics, including continuous glucose monitoring and insulin pumps. Treatment options related to type 1 diabetes and several case studies are discussed.

Course Format


Course Syllabus

I.              Introduction
II.           Epidemiology
III.        Prediabetes versus Diabetes
1.   Diabetes Type 2 versus Type 1
IV.         Type 1 Diabetes
1.   Case Study: Dietary Control in Type 1 Diabetes
2.   Case Study: Type 1 Diabetes, Uncontrolled
V.            Diabetes Type 1 Treatments
1.   Rapid-acting Insulin
2.   Short-acting Insulin
3.   Intermediate Insulin
4.   Long-acting Insulin
5.   Pre-mixed Insulin
6.   Oral Agents
VI.         Fast-acting Insulin
1.   Humalog ® (lispro)
2.   Novolog ® (aspart)
3.   Case Study: Bedtime Hyperglycemia
4.   Apidra® (glulisine)
5.   Inhaled Insulins
6.   Afreza® (inhaled insulin)
VII.       Short-acting Insulin
1.   Regular R or Novolin R
2.   Case Study: Type 1 Diabetes and Elevated A1c
3.   Levemir® (insulin detemir)
VIII.    Method of Monitoring the Blood Sugar
1.   Continuous Glucose Monitoring
2.   Case Study: Insulin Algorithm
3.   Case Study: Chaotic Glucose Pattern
4.   Case Study: Consistency in Glucose Pattern
5.   Case Study: Switching from NPH to Detemir Insulin
6.   Case Study: Late Afternoon Hypoglycemia
7.   Case Study: Late Morning Hyperglycemia
8.   Case Study: Evening Hyperglycemia
IX.         Summary


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