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Coronavirus Disease 2019: Diabetes and Obesity

Author: Noah Carpenter, MD and Dana Bartlett, RN, BSN, MSN, MA, CSPI

CE: 2 hours Pharmacology: 0.5 hour
Rated 4.7 out of 5.0 based on 1220 reviews

Course Summary

Coronavirus disease 2019 is a potentially serious condition caused by SARS-CoV-2. Medical experts are studying important questions regarding  diabetic patients who are also infected with SARS-CoV-2. It is important for clinicians to know whether diabetic patients are more likely than non-diabetic patients to have COVID-19, and whether the disease will be more serious because of the presence of diabetes. These patients may also be diagnosed with diabetic ketoacidosis, hyperosmolar hyperglycemic state, or euglycemic diabetic ketoacidosis. Treating hyperglycemia is one of the biggest challenges  in patients who have COVID-19. Diabetic patients may require admission to an ICU and they tend to have a longer hospital stay. Treatment of a diabetic patient with COVID-19 also involves decisions regarding the use or continued use of antidiabetic medications.

Course Format


Course Syllabus

I.    Introduction

II.    Overview of COVID-19 Pandemic

III.    Epidemiology: COVID-19, Diabetes and Obesity

IV.    Infection and Pathophysiology

1. ACE2 Expression
2. Dysregulated Immune Response
3. Cytokine Storm
4. Pulmonary Dysfunction
5. Glycemic Control and Insulin Resistance

V.         Glycemic Complications

1. Diabetic Ketoacidosis and Hyperosmolar Hyperglycemic State
2. Hyperglycemia and Insulin Resistance
3. Euglycemic Diabetic Ketoacidosis

VI.    Can COVID-19 Cause Diabetes?

VII.         Treatment of Uncomplicated Diabetes

1. Basic Care
2. Glycemic Control: Glucose Level
3. Pharmacotherapy

VIII.         Glycemic Control in Comorbid Diabetes and COVID-19

1. Metformin
2. Sulfonylureas
3. Dipeptidyl peptidase-4 (DPP-4) inhibitors
4. GLP-1 receptor agonists
5. Thiazolidinediones
6. SGLT2 Inhibitors
7. Insulin

IX.         Treatment of Diabetic Complications

1. Nutrition
2. Obesity

X.    Summary


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