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Author: Dana Bartlett, BSN, MSN, MA, CSPI
(Click author's name for bio)

CE: 2.5 hours Pharmacology: 2.5 hours
Rated 4.7 out of 5.0 based on 2538 reviews

Course Summary

Bupropion is an antidepressant with stimulant effects and pharmacological properties that include action as a selective inhibitor of catecholamines reuptake and a noncompetitive antagonist of nicotinic acetylcholine receptors. It is well accepted as treatment for smoking cessation. There is significant misuse potential of bupropion as a cathinone derivative (a beta-ketone amphetamine analogue) with dopaminergic and noradrenergic effects. In large quantities, bupropion may achieve an amphetamine-like high and some have used bupropion recreationally by oral, nasal and intravenous administration.

Course Format


Course Syllabus

I.              Introduction

II.           Pharmacological Profile

1.         Drug Category

2.         Mechanism of Action

3.         Labeled Uses

4.         Off-Label Uses

5.         Dosing Forms

6.         Dosing Adjustment: Geriatric Patients

7.         Dosing Adjustment: Hepatic Impairment

8.         Dosing Adjustment: Renal Impairment

9.         Contraindications

10.     US Boxed Warning

11.     Adverse Effects

12.     Warnings

13.     Pregnancy and Breastfeeding

14.     Drug-drug Interactions

III.        Clinical Pearls: Bupropion

IV.         Bupropion Overdose

V.            Case Study: Bupropion

1.   Discussion

VI.         Summary


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