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Asenapine

Author: Dana Bartlett, BSN, MSN, MA, CSPI
(Click author's name for bio)

CE: 2.5 hours Pharmacology: 2.5 hours
Rated 4.7 out of 5.0 based on 187 reviews

Course Summary

Asenapine is a second-generation, atypical, antipsychotic medication that is known to be effective in the treatment of bipolar 1 disorder and schizophrenia. The pharmacological profile and labeled uses and administration of asenapine make it a unique antipsychotic drug of choice in emergency psychiatry cases, the pediatric population and for the maintenance treatment of mixed mood states. Individuals experiencing a manic episode are often treated with benzodiazepines and antipsychotics, although the specific effects of antipsychotics on hostility and aggression in patients with schizophrenia or bipolar disorder have received special attention by emergency clinicians. Asenapine is a non-invasive, fast-dissolving sublingual tablet. Clinical trials have used drug rating scales to help determine how well asenapine treats patient hostility and agitation during a manic or mixed episode.

Course Format

Homestudy

Course Syllabus

I. Introduction
II. Pharmacological Profile

1.   Category
2.   Mechanism of Action
3.   Labeled Uses
4.   Dosing
5.   Dosing Adjustment: Geriatric Patients
6.   Dosing Adjustment: Hepatic Impairment
7.   Dosing Adjustment: Renal Impairment
8.   Administration
9.   Available Forms
10.                 US Boxed Warning
11.                 Contraindications
12.                 Adverse Effects
13.                 Warnings and Precautions
14.                 Pregnancy and Breastfeeding
15.                 Drug-Drug Interactions

III. Clinical Pearls: Asenapine

1.   Asenapine Overdose

IV. Case Study: Asenapine

1.   Case Study 1: Bipolar Disorder with Mania
2.   Case Study 1: Discussion
3.   Case Study 2: Bipolar Disorder
4.   Case Study 2: Discussion

V. Summary

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