Course Summary

The angiotensin receptor blockers are one of the most widely used antihypertensives. They are a first-line choice for treating primary hypertension in the general non-black population and for people greater or equal to 18-years of age who have hypertension and chronic kidney disease. The use of angiotensin receptor blockers is well tolerated as monotherapy, and as combination therapy with other antihypertensive medications. There is no antidote for ARB poisoning. The recommended treatment is to use standard and supportive care.

Course Format

Homestudy

Course Syllabus

•  I.       Introduction
•  II.       ARBS and Renin-Angiotensin System
• III.       Pharmacological Profile of ARB Medication
  • 1.   Pharmacological Category
  • 2.   Mechanism of Action
  • 3.   Uses
  • 4.   US Boxed Warning
  • 5.   Contraindications
  • 6.   Warnings
  • 7.   Adverse Effects
  • 8.   Use During Pregnancy and Breastfeeding
  • 9.   Dietary Considerations
• IV.      ARBS and Hypertension
• V.      ARB Medication and Heart Failure
• VI.      ARB Medication and Diabetic Nephropathy
• VII.      ARB Medication and Angioedema
  • 1.   Etiology
  • 2.   Incidence
  • 3.   ARB-Induced Angioedema and ACE-Induced Angioedema
  • 4.   Treatment
• VIII.     ARB Overdose
  • 1.   Case Report 1
  • 2.   Case Report 2
  • 3.   Case Series
• IX.      Treatment
• X.       Summary

Authors

Dana Bartlett, RN, BSN, MSN, MA, CSPI

Dana Bartlett is a professional nurse and author. His clinical experience includes 16 years of ICU and ER experience and over 27 years as a poison control center information specialist. Dana has published numerous CE and journal articles, written NCLEX material, textbook chapters, and more than 100 online CE articles, and done editing and reviewing for publishers such as Elsevier, Lippincott, and Thieme. He has written widely on the subject of toxicology and was a contributing editor, toxicology section, for Critical Care Nurse journal. He is currently employed at the Connecticut Poison Control Center. He lives in Wappingers Falls, NY.

Kellie Wilson, PharmD

Kellie Wilson is a Doctor of Pharmacy practicing in Anaconda, Montana, where she lives with her husband and four children. She attended the University of Montana in Missoula where she graduated in 2009 with a doctorate in pharmacy. She later worked in Boise, Idaho for a large, retail pharmacy for 2 years, and then returned home to Montana to oversee an independently owned retail and long-term care pharmacy in Anaconda. As an independent retail pharmacist she has become very involved in psychiatric pharmacy for two major behavioral health organizations that are located around all of Montana. Kellie’s passion is retail pharmacy because she enjoys the interactions with customers as well as the challenges and rewards of staying current with the continuous changes in the pharmacy field.