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Advanced Practice: Cariprazine

Author: Richard "Cole" Daniels, PharmD, BCPS

CE: 2.5 hours
Rated 4.8 out of 5.0 based on 3134 reviews

Course Summary

Cariprazine is an atypical, second-generation antipsychotic medication that is primarily used to treat schizophrenia and bipolar disorder. It functions by modulating the activity of certain neurotransmitters in the brain, specifically dopamine and serotonin receptors. Cariprazine has been shown to be effective in reducing the symptoms of these mental health conditions, including hallucinations, delusions, and mood disturbances. Unlike older antipsychotic medications, cariprazine is associated with a lower risk of certain adverse effects, such as weight gain and metabolic disturbances. However, certain adverse effects unique to antipsychotics exist, namely akathisia, sedation, extrapyramidal symptoms, and nausea. When taken in overdose, fatalities are rare. There is no antidote for cariprazine overdose, and treatment should be symptomatic and supportive.

Course Format


Course Syllabus

  1. Introduction
  1. Pharmacological Profile, Dosing, Uses, and Warnings

Dosage Forms, Recommended Dosing, and Dosing Adjustments

  1. Schizophrenia, Bipolar Disorder, Major Depression, and Dementia-related Psychosis
  1. Bipolar 1 Disorder and Major Depression
  2. Dementia-Related Psychosis
  1. Drug Warnings, Contraindications, and Adverse Effects
  1. Cardiovascular
  2. Central Nervous System
  3. Metabolic Challenges, Weight Gain, and Dysphagia/Aspiration
  4. Hematologic
  5. Hyperprolactinemia
  6. Neuroleptic Malignant Syndrome
  7. Temperature Regulation
  8. Seizure Disorder and Falls
  9. Suicidal Ideation and Behavior
  10. Pregnancy and Breastfeeding
  1. Cariprazine Drug Interactions and Overdose
  1. Case Study and Research Review: Treatment of Schizophrenia and Bipolar Disorder

Research Review

  1. Summary


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