Thiothixene Treatment for Schizophrenia: Anticholinergic and Dopamine Blocking Action
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South Carolina Information
Pharmacotherapeutics Credits: 2.5
Related to prescribing controlled substances: 0
Course Summary
Thiothixene is an antipsychotic medication that belongs to the class of thioxanthenes. It is primarily used to treat schizophrenia and other psychotic disorders, effectively alleviating symptoms such as hallucinations, delusions, and disorganized thinking. Thiothixene blocks certain neurotransmitter receptors, particularly dopamine receptors, in the brain, thereby reducing the excess dopamine activity associated with psychotic conditions. Though effective, thiothixene may cause side effects such as drowsiness, dizziness, and movement disorders. The use of thiothixene has significantly declined in recent decades with the advent of the newer atypical antipsychotics, however, it continues to be manufactured and used in many countries worldwide.
Course Format
Homestudy
Course Syllabus
Introduction
Pharmacological Profile and Uses
Dosing and Available Forms
Dosing Adjustment: Geriatric Patients
Dosing Adjustment: Hepatic and Renal Impairment
Thiothixene Contraindications, Adverse Effects, and Warnings
Potential Adverse Effects
Pregnancy and Breastfeeding
Drug-Drug Interactions and Withdrawal/Discontinuation
Thiothixene Overdose
Case Study: Thiothixene Wrongful Administration
Summary