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Targeting Brain Structures and Novel Therapies to Manage Parkinson’s Disease

Author: Jassin M. Jouria, MD
(Click author's name for bio)

CE: 3 hours Pharmacology: 0.5 hour
Rated 4.7 out of 5.0 based on 697 reviews

Course Summary

While the cause, risks and characteristics of Parkinson’s disease are well defined in recent movement disorder diagnostic guidelines, there is no definitive test that can confirm a diagnosis of Parkinson’s disease during a person's life. The diagnosis of Parkinson’s disease remains a clinical one, confirmed only after autopsy. Clinicians treat based on clinical observation and close follow up of symptoms, and must be well informed of the changing medical options to help prolong and improve quality of life for those diagnosed with the disease. Successful pharmacotherapy of Parkinson’s disease depends on the ability of clinicians to accurately recognize characteristic signs of the disease, and to successfully function within an interdisciplinary team that includes primary care and neurology medicine to arrive at the right diagnosis. This is the third in a three part series.

Course Format


Course Syllabus

I. Introduction

II. Managing Advanced Parkinson’s Disease

1. Motor Fluctuations

2. Dyskinesia

3. Nausea

III. Choice Of Therapy For Dyskinesia In Parkinson’s Disease

1. Patient-related Factors

IV. Psychiatric Comorbidities

1. Cognitive Impairment

IV. Dementia In Parkinson’s Disease V. Pharmacologic Treatment For Neuropsychiatric Symptoms

1. Neuropsychiatic Comorbidities

VI. Non-Pharmacological Therapies In Parkinson’s Disease

1. Cognitive Behavioral Therapy

2. Cognitive Training

3. Repetitive Transcranial Magnetic Stimulation

4. Neuroprotective Therapy

5. Deep Brain Stimulation

6. Neuroablative Therapy

VII. Alternative And Complementary Therapies For PD

1. Tai Chi and Qigong

2. Acupuncture and Moxibustion

3. Massage and Other Manual Therapies

4. Botanical Therapies

5. Dietary Considerations

VIII. Physical And Exercise Therapy IX. Novel Therapies: Agents And Targets

1. Adenosine Receptor Antagonists

2. Glutamate Release Inhibitors

3. Neural Transplants

4. Gene Therapy

X. Future Directions In Parkinson’s Disease 

XI. Summary


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