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Author: Noah Carpenter, MD and Dana Bartlett, RN, BSN, MSN, MA, CSPI

CE: 2.5 hours Pharmacology: 0.5 hour
Rated 4.7 out of 5.0 based on 7270 reviews

Course Summary

Rhabdomyolysis is often a self-limiting condition that involves the rapid destruction of muscle tissue that affects the kidneys as muscle protein passes through to the urine. It is a syndrome that responds well to supportive care, but rhabdomyolysis can cause serious complications such as acute kidney injury and compartment syndrome, as well as death. The etiologies, pathophysiology, and complications of rhabdomyolysis are complex and the incidence high enough that health clinicians at all levels of experience would benefit from ongoing review of the research and case studies supporting safe and appropriate care.

Course Format


Course Syllabus

I. Introduction

II. Etiology

1. Traumatic Rhabdomyolysis
2. Exertional Rhabdomyolysis
3. Non-traumatic/Non-exertional Rhabdomyolysis

III. Pathophysiology

IV. Symptoms of Rhabdomyolysis

V. Diagnosis

Laboratory Testing

VI. Complications of Rhabdomyolysis

VII. Treatment of Rhabdomyolysis

1. Intravenous Fluid Resuscitation
2. Alkaline Diuresis, Mannitol and Loop Diuretics

VIII. Case Study: Rhabdomyolysis

IX. Summary


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