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Parkinson’s Disease - Symptoms And Pharmacological Treatment

Author: Jassin M. Jouria, MD
(Click author's name for bio)

CE: 3 hours Pharmacology: 1 hour
Rated 4.7 out of 5.0 based on 1541 reviews

Course Summary

While the cause, risks and characteristics of Parkinson’s disease are well defined in recent movement disorder diagnostic guidelines, there is no definitive test that can confirm a diagnosis of Parkinson’s disease during a person's life. The diagnosis of Parkinson’s disease remains a clinical one, confirmed only after autopsy. Clinicians treat based on clinical observation and close follow up of symptoms, and must be well informed of the changing medical options to help prolong and improve quality of life for those diagnosed with the disease. Successful pharmacotherapy of Parkinson’s disease depends on the ability of clinicians to accurately recognize characteristic signs of the disease, and to successfully function within an interdisciplinary team that includes primary care and neurology medicine to arrive at the right diagnosis. This is the second in a three part series.

Course Format


Course Syllabus

I                Introduction

II             Diagnosis Of Parkinson’s Disease: A Review

1.   Resting Tremor

2.   Rigidity

3.   Bradykinesia

4.   One-Year Rule

III           Subtypes Of Parkinson’s Disease

1.   Onset of Parkinson’s Disease

2.   Key Features of the MDS Diagnostic Criteria

3.   MDS-UPDRX Clinimetric Assessment

IV            Treatment Of Parkinson’s Disease

1.   Symptom Progression and Medication

2.   Dopaminergic Neurons

3.   Main Functions of Dopamine

4.   Dopamine Receptors

V              Pharmacology In The Treatment Of Parkinson’s Disease

1.   Levodopa

2.   Sinemet

3.   Duopa

4.   Early Parkinson’s Disease and Dopamine Agonists

5.   Apomorphine

6.   Pramipexole

7.   Ropinirole

8.   Amantadine

9.   Rotigotine

10.        Anticholinergic Drugs

11.        Trihexyphenidyl

12.        Benztropine mesylate

13.        Monoamine Oxidase-B Inhibitors

14.        Selegiline

15.        Rasagiline

16.        Safinamide

17.        Acetylcholinesterase Inhibitors

18.        Donepezil

19.        Rivastigmine

VI            Managing Motor Fluctuations In Parkinson’s Disease

VII         Summary


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