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Oxcarbazepine

Author: Dana Bartlett, BSN, MSN, MA, CSPI
(Click author's name for bio)

CE: 2.5 hours Pharmacology: 2.5 hours
Rated 4.7 out of 5.0 based on 217 reviews

Course Summary

Oxcarbazepine is an anticonvulsant that has a labeled use as a monotherapy or as an adjunctive treatment for patients who have focal seizures. Oxcarbazepine is an analogue of carbamazepine, and the drug rapidly and almost completely converts to enantiomers with equal biologic activity, yet retains the efficacy of carbamazepine. Some medical reviews report that oxcarbazepine has more favorable metabolic, pharmacokinetic, tolerability, and safety profiles than carbamazepine. However, some reports indicate that at higher doses there can be poor tolerability of oxcarbazepine, specifically in the immediate release form.

Course Format

Homestudy

Course Syllabus

I.              Introduction

II.           Pharmacological Profile

1.         Drug Category

2.         Mechanism of Action

3.         Uses

4.         Available Forms

5.         Dosing

6.         Dosing Adjustment: Geriatric

7.         Dosing Adjustment: Hepatic Impairment

8.         Dosing Adjustment: Rental Impairment

9.         Contraindications

10.     Adverse Effects

11.     Warnings

12.     Pregnancy and Breastfeeding

13.     Drug Interactions

III.         Clinical Pearls: Oxcarbazepine

IV.          Oxcarbazepine Overdose

V.            Case Study

1.   Discussion

VI.          Summary

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