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Opioid Use Disorder - Medication Treatment

Author: Abimbola Farinde, PhD, PharmD and Dana Bartlett, RN, BSN, MSN, MA, CSPI

CE: 2.5 hours Pharmacology: 2.5 hours
Rated 4.7 out of 5.0 based on 1321 reviews

Course Summary

Naloxone is available for acute opioid overdose or emergency. It is also useful in a maintenance program in a take-home form. Take-home naloxone requires training in the prevention of overdose. Naltrexone has been proven to be a safe, effective, and well-tolerated treatment for patients who have opioid use disorder. Treatment with naltrexone requires patients to withdraw from opioids before naltrexone therapy can be initiated. For patients who complete opioid withdrawal and detoxify, naltrexone appears to be an effective long-term treatment option for opioid use disorder.

Course Format


Course Syllabus

I.      Introduction
II.      Overview of Opioids
III.      Naloxone
1.        Available Forms and Action
2.        Pharmacokinetics
3.        Dose
4.        Contraindications and Adverse Reactions
5.        Warnings
IV.      Naloxone: Clinical Pearls
1.        Acute Opioid Intoxication
2.        Route of Administration
3.        Proper Dosing
4.        Adverse Effects and Warnings
5.        Naltrexone
6.        Available Forms and Action
7.        Pharmacokinetics
8.        Dose
9.        Contraindications
10.      Adverse Effects
11.      Warnings
12.      Opioid Overdose
13.      Pregnancy and Breastfeeding
V.      Naltrexone: Clinical Pearls
1.        Labeled Use: Alcohol Use Disorder
2.        Labeled Use: Opioid Use Disorder
3.        Adverse Effects – Laboratory Studies
4.        Laboratory Test Interference
5.        Opioid Overdose
6.        Suicide Issues/Depression
7.        Pregnancy and Breastfeeding
8.        Case Study: Naltrexone
VI.      Summary


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