I. Introduction
II. Overview of Opioids
III. Naloxone
1. Available Forms and Action
2. Pharmacokinetics
3. Dose
4. Contraindications and Adverse Reactions
5. Warnings
IV. Naloxone: Clinical Pearls
1. Acute Opioid Intoxication
2. Route of Administration
3. Proper Dosing
4. Adverse Effects and Warnings
5. Naltrexone
6. Available Forms and Action
7. Pharmacokinetics
8. Dose
9. Contraindications
10. Adverse Effects
11. Warnings
12. Opioid Overdose
13. Pregnancy and Breastfeeding
V. Naltrexone: Clinical Pearls
1. Labeled Use: Alcohol Use Disorder
2. Labeled Use: Opioid Use Disorder
3. Adverse Effects – Laboratory Studies
4. Laboratory Test Interference
5. Opioid Overdose
6. Suicide Issues/Depression
7. Pregnancy and Breastfeeding
8. Case Study: Naltrexone
VI. Summary