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Loop Diuretics

Author: Dana Bartlett, BSN, MSN, MA, CSPI
(Click author's name for bio)

CE: 3 hours Pharmacology: 3 hours
Rated 4.7 out of 5.0 based on 2482 reviews

Course Summary

Loop diuretics are potent diuretics that are used to control edema in various clinical conditions. They inhibit sodium reabsorption in the kidney, and increase urinary sodium and water excretion. Common loop diuretics, such as furosemide, may be administered through the oral or intravenous route. There are both benefits and risks of a loop diuretic, such as in cases of chronic kidney disease and potential side effects. To maximize the efficiency of a loop diuretic, clinicians must clearly understand the mode of drug delivery, bioavailability and required dosage of drug administration.

Course Format


Course Syllabus

I.              Introduction

II.           Pharmacological Profile of Loop Diuretics

1.   Category

2.   Uses

3.   Available Forms

4.   Dosing

5.   Mechanism of Action

6.   U.S. Boxed Warning

7.   Contraindications

8.   Disease-related Concerns

9.   Adverse Effects

10.        Dosing Adjustments: Hepatic Impairment

11.        Dosing Adjustments: Rental Impairment

12.        Use During Pregnancy and Lactation

13.        Dietary Recommendations

14.        Use in the Elderly: Beers Criteria

III.         Loop Diuretics For The Treatment Of Edema

1.   Heart Failure and Edema

2.   Pulmonary Edema

3.   Cirrhosis and Edema

4.   Renal Disease and Edema

IV.          Hypertension And Chronic Kidney Disease: Role Of Loop Diuretics

V.            Summary


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