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Diabetic Ketoacidosis

Author: Noah Carpenter, MD and Dana Bartlett, RN, BSN, MSN, MA, CSPI

CE: 2.5 hours Pharmacology: 0.5 hour
Rated 4.7 out of 5.0 based on 23999 reviews

Course Summary

Diabetic ketoacidosis is an acute complication of diabetes mellitus, which requires prompt, aggressive, treatment. Complications of diabetic ketoacidosis throughout the age spectrum and during pregnancy require a close evaluation of symptoms, testing, treatment and outcomes to treatment. Anyone with diabetes, regardless of age or gender, can develop ketoacidosis. Guidelines exist that guide diabetes health teams in the clinical care of the diabetic patient. Appropriate and timely treatment can reduce diabetic ketoacidosis complications and patients can recover to full health.

Course Format


Course Syllabus

I.  Introduction
II.  Diabetic Ketoacidosis: a Metabolic Disorder
III.  Epidemiology
IV.  Glucose, Insulin, and Diabetes: A Brief Review
1.   Glucose and Energy
2.   Type 1 and Type 2 Diabetes Classification System: Out of Date?
V.  Pathophysiology of DKA
1.   Pathophysiology, Signs and Symptoms of DKA
2.   Precipitating Causes
VI.  Clinical Signs and Symptoms of DKA
VII.  Diagnosis of DKA
1.   Laboratory Tests
2.   Hyperkalemia
3.   Hyponatremia
4.   Other Electrolytes
5.   Amylase, Lipase and Hepatic Transaminases
6.   Leukocytosis
7.   Serum Osmolality and Renal Function Studies
8.   Troponin Levels
9.   Euglycemic DKA
VIII.  Gestational Diabetes and DKA
1.   Risk Factors
2.   Insulin Resistance
3.   Ketosis
4.   Clinical Presentation
IX.  Atypical Antipsychotics and DKA
X.  Complications of DKA
1.   Cerebral Edema
XI. Assessment and Treatment
1.   Fluid Replacement
2.   Electrolyte Imbalances
3.   Insulin Therapy
4.   Acid-Base Disturbances and Bicarbonate Therapy
5.   Cerebral Edema
XII.  Monitoring, Clinical Care and Prevention
1.   Clinical Care and Education
2.   Access to Medical Care
3.   Lack of Education
4.   Emotional Acceptance and Non-compliance
XIII.  Case Studies: Diabetic Ketoacidosis
1.   Case 1: Euglycemic DKA with Dapagliflozin
2.   Case 2: Acute Mountain Sickness and DKA
3.   Case 3: Pediatric DKA and Cerebral Edema
XIV.  Summary


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