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Buprenorphine-Naloxone Treatments for Opioid Use Disorder

Author: Kellie Wilson, PharmD
(Click author's name for bio)

CE: 2.5 hours Pharmacology: 2.5 hours
Rated 4.7 out of 5.0 based on 10345 reviews

Course Summary

An opioid use disorder is a complex process that is caused by repeated exposure to the drugs, and there are genetic, psychological, social, and physical factors that contribute to its development. Repeated use of an opioid provides strong physical and psychological motivators to continue taking it and strong physical and psychological discouragements to stop. Buprenorphine-naloxone is discussed in terms of the treatment of opioid substance use with the primary goal of treatment being to discourage patients from using. Varied methods of drug use and existing treatment options aimed at prevention as well as the clinical risks and side effects of buprenorphine-naloxone treatment are reviewed.

Course Format


Course Syllabus

I.        Introduction
II.       Opioid Use and Clinical Effects
1.   Opioid Mechanism of Action and Clinical Effects
III.      Prescribing Opioids and Hazards of Use
IV.      Pharmacological Profile of Buprenorphine and Naloxone
1.  Buprenorphine
2.  Naloxone
V.       Opioid Use Disorder
1.   Physiological Effects
2.   Withdrawal
3.   Medically Supervised Opioid Withdrawal
4.   Steps of Buprenorphine-Naloxone Use
5.   Medication-Assisted Treatment (MAT)
VI.     Buprenorphine Overdose and Pediatric Exposure
1.   Vivitrol
2.   Evzio
3.   Case Study: Buprenorphine-Naloxone Use and Medical Treatment
4.   Case Study 2: Suboxone Treatment
5.   Case Study 3: Suboxone Treatment
VII.      Summary


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