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Blood Transfusions - Overview of Safe and Appropriate Treatment

Author: Dana Bartlett, BSN, MSN, MA, CSPI
(Click author's name for bio)

CE: 3 hours Pharmacology: 0.5 hour
Rated 4.7 out of 5.0 based on 5307 reviews

Course Summary

Being able to replace blood and blood components that a patient has lost or is unable to produce is a specialized section of medicine that can be life saving. With the aid of donor blood, or even sometimes the patient’s own blood that has been previously banked, health professionals in transfusion medicine can follow a safe strategy to treat patients who have lost blood to illness or injury. The different types of blood products, the requirements for performing a transfusion, and how to recognize and respond to complications of the transfusion process are discussed.

Course Format


Course Syllabus

I.     Introduction
II.    Overview of National Guidelines
III.   Transfusions of Blood and Blood Components
1.        Packed Red Blood Cell Transfusion
2.        Proper Use of RBC Transfusion
3.        Transfusion of Other Blood Components
IV.   Principles of Pre-Transfusion Testing and Transfusions
1.        Donor Requirements
2.        Electronic Crossmatching
3.        Blood and Blood Component Pre-Testing
V.    ABO Inheritance
1.        ABO System
2.        Rh System
VI.   Whole Blood Compatibility
1.        Pre-Transfusion Testing
2.        Immune Globulins
3.        Alternatives to Transfusion
4.        Transfusion Technique
5.        Observation of the Transfusion Patient
6.        Emergency Release of Blood Products
VII.  Indications for Blood Transfusions
1.        Massive Acute Hemorrhage
2.        Chronic Hemorrhage
3.        Traumatic Hemolytic Anemia
4.        Deficient Erythropoiesis Hypochromic-Microcytic Anemias
5.        Macrocytic Anemias
6.        Hemolytic Anemias
7.        Autoimmune Hemolytic Anemias
8.        Paroxysmal Nocturnal Hemoglobinuria
9.        Hereditary Spherocytosis and Elliptocytosis
10.      Metabolic Disorders with Hemolytic Anemia
11.      Hemoglobinopathies
VIII.  Complications of Transfusions
1.        Acute Hemolytic Transfusion Reactions
2.        Delayed Hemolytic Transfusion Reactions
3.        Transfusion-Related Lung Injury
4.        Transfusion-Associated Circulatory Overload
5.        Other Transfusion Reactions
6.        Massive Transfusion Complications
IX.   Risk of Post Transfusion Infection
1.        Bacterial Infections
2.        Viral Infections
X.    Therapeutic Apheresis
1.        Cytapheresis
2.        Photophoresis
3.        Plasma Exchange
XI.   Blood Transfusion and Intrauterine Fetal Blood Reactions
1.        Rh Disease (Erythroblastosis Fetalis)
2.        Post-transfusion Purpura
3.        RBC Transfusion and Sepsis
4.        Basic Care of Transfusion Reaction
XII.   Case Study: Acute Hemolytic Transfusion Reaction
XIII.  Summary


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