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Barrett’s Esophagus

Author: Noah H. Carpenter, MD

CE: 2.5 hours Pharmacology: 0.5 hour
Rated 4.7 out of 5.0 based on 9354 reviews

Course Summary

Barrett’s esophagus is a complication of gastroesophageal reflux disease, which involves reflux of gastric contents that damages the normal lining of the lower esophagus. A different type of lining (intestinal metaplasia with goblet cells) replaces the normal esophageal lining and is known as Barrett’s esophagus. A serious, potential complication of Barrett's esophagus is the abnormal esophageal lining, which develops over time and can develop early precancerous changes. The early changes may progress to advanced precancerous cellular changes, and finally to esophageal cancer, although this final stage is uncommon. When it does progress to cancer, adenocarcinoma of the esophagus is the form of esophageal cancer typically seen in Barrett’s esophagus. Updated screening guidelines to identify the presence of Barrett’s esophagus are needed because relying on symptoms such as heartburn or gastroesophageal reflux are inadequate.

Course Format


Course Syllabus

I.    Introduction

II.    Epidemiology

III.    Complications of Barrett’s Esophagus

IV.    Risk Factors of Barrett’s Esophagus

1. Chronic Heartburn, Acid Reflux and Erosive Esophagitis
2. Age, Gender, Race and Geography
3. Obesity and Smoking

V.    Long-segment and Short-segment Barrett’s Esophagus

VI.    Diagnosis of Barrett’s Esophagus

VII.    Treatment of Barrett’s Esophagus

1. Surveillance Endoscopy
2. Gastroesophageal Reflux Disease

VIII.         High-grade Dysplasia and Treatment

1. Esophagectomy
2. Endoscopic Mucosal Resection
3. Radiofrequency Ablation
4. Photodynamic Therapy
5. Endoscopic Spray Cryotherapy

IX.         Screening Guidelines

X.    Case Study: GERD Progression to Barrett’s Esophagus


XI.    Summary


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