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Antipsychotics and Neuroleptic Malignant Syndrome

Author: Jassin M. Jouria, MD
(Click author's name for bio)

CE: 3.5 hours Pharmacology: 0.5 hour
Rated 4.7 out of 5.0 based on 2357 reviews

Course Summary

Neuroleptic Malignant Syndrome is both rare and potentially fatal. Health clinicians need to recognize signs and symptoms and ask the right questions to make an accurate diagnosis and begin treatment. While this condition is not entirely understood, its symptoms are recognizable and typically easily resolved with little or no long-term impact to the patient when caught early. A treatment and management plan must be implemented. Pharmacotherapy has not been consistently effective in all case reports of neuroleptic malignant syndrome. In contrast, electroconvulsive therapy may be effective. A key step in the management of neuroleptic malignant syndrome is the initiation of supportive medical therapy.

Course Format


Course Syllabus

I.       Introduction

II.      Overview Of Neuroleptic Malignant Syndrome

A.   Dopamine Receptors and NMS

III.    Neuroleptic Drugs

A.   Neuroleptic Drugs and NMS

B.   Neuroleptics or Antipsychotics as Sole Cause of NMS

IV.     Clinical Presentation And Diagnosis Of NMS

A.   Diagnosing NMS

B.   Distinguishing NMS from Serotonin Syndrome

C.   NMS and Malignant Hyperthermia

D.   Other Disorders Mistaken for NMS

E.   Drugs Causing Symptoms Resembling NMS

V.      NMS And Serotonergic Receptors

VI.     Summary


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